ANSWER: The appropriate time to take D-mannose will depend on your individual needs and the reason for taking it.
If you are taking D-mannose to prevent urinary tract infections (UTIs), it may be helpful to take it at the same time each day to establish a regular routine. Some people find it easiest to take D-mannose first thing in the morning, while others prefer to take it in the evening before bed. .
It is important to drink plenty of water throughout the day to help flush bacteria from the urinary tract.
If you are taking D-mannose to treat an existing UTI, it may be helpful to take it at evenly spaced intervals throughout the day, as recommended by your healthcare provider. Consult with your provider to determine the best time and schedule for taking D-mannose